Endocrine Abstracts

Aim: Neopterin has been found to be associated with disease activity in various infectious, inflammatory, and autoimmune diseases. It is an indicator of immune response as it is released after activation of monocytes and macrophages by IFN-γ. It was aimed to measure neopterin levels in Graves’ disease, which is a T cell-mediated autoimmune disease of the thyroid gland.Materials and Methods: Twelve healthy individuals (6 women, 6 men), 13 Graves...

Background and aims: Diabetes is an endocrinological disease with high incidence and important complications. Studies indicate that by 2030, diabetes will affect approximately 366 million people around the world. Neopterin is produced by activated monocyte-macrophages with the induction of interferon gamma and it is accepted as a biomarker of immune activation. Elevated neopterin levels in biological fluids can be observed in neurological, cardiovascular and autoimmune disorde...